Cancer Evolution: Genetic and Epigenetic Evolution of Hematopoietic Neoplasms

Dr rer nat in Biology, Mathematics or Medicine
PhD in Medical Research (PhD med res in Medicine)
In cooperation with
TU München, LMU Klinikum, TUM Klinikum rechts der Isar, Helmholtz Zentrum München
Course language(s)
Admission semester
Any time
Application deadline
The IRTG 1243 graduate programme is embedded in the CRC 1243 research consortium; doctoral candidates working on these projects are eligible for membership in the IRTG.
Course content
The Collaborative Research Center SFB 1243 Cancer Evolution (Genetic and Epigenetic Evolution of Hematopoietic Neoplasms) studies different aspects of cancer development in an evolutionary framework, in particular, the grounds for the poor prognosis of acute myeloid leukaemia and indolent lymphomas. Using interdisciplinary approaches, the projects aim to decipher molecular mechanisms as well as measure the evolution of genetic, epigenetic, and transcriptional heterogeneity in patients, mice, and cellular systems. The projects also aim to quantify relevant parameters by applying computational models.
Educational organisation
The Integrated Research Training Group (IRTG) 1243 offers an interdisciplinary graduate training programme covering topics ranging from molecular and cellular biology and computational biology to clinical haematology. Committed to supporting members during their research projects, the IRTG 1243 offers training in state-of-the-art techniques, including genetic engineering, single cell genomics, high-throughput sequencing, and computational data analysis as well as in diverse professional skills. Research projects are supervised collaboratively by clinicians, molecular biologists, and population geneticists as well as computational and evolutionary biologists. Doctoral researchers are encouraged to participate in shaping individual curricula, encouraging the scientific independence and development necessary for successful careers in science.
General promotion / funding
German Research Foundation
Tuition fees
No tuition
Enrolment fees
Approx. 130 EUR per semester
Costs of living
Living costs (including accommodation and health insurance) in Munich range from 800 to 1,000 EUR per month.
Job opportunities
Doctoral positions are salaried positions, based on institutional regulations.
Language requirements
Members are expected to have excellent written and spoken English. Proficiency test scores are currently not required.
Academic requirements
Master’s degree in biology, bioinformatics, biochemistry, mathematics
Medical degree

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